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1 year ago

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Real time monitoring of cold Ca2+ dependent transcription and its modulation by NCX inhibitors - Scientific Reports

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Real time monitoring of cold Ca2+ dependent transcription and its modulation by NCX inhibitors - Scientific Reports

Real-time monitoring of cellular temperature responses is an important technique in thermal biology and drug development. Recent study identified that Na+/Ca2+ exchanger (NCX)-dependent Ca2+ influx transduces cold signals to circadian clock in mammalian cultured cells. The finding raised an idea that cellular responses to the cold signals can be analyzed by monitoring of clock gene expression.

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Real time monitoring of cold Ca2+ dependent transcription and its modulation by NCX inhibitors - Scientific Reports

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Real time monitoring of cold Ca2+ dependent transcription and its modulation by NCX inhibitors - Scientific Reports

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