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Naturally occurring spike mutations influence the infectivity and immunogenicity of SARS-CoV-2 - Cellular & Molecular Immunology

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Naturally occurring spike mutations influence the infectivity and immunogenicity of SARS-CoV-2 - Cellular & Molecular Immunology

Mutations in SARS-CoV-2 variants of concern (VOCs) have enhanced transmissibility and immune evasion with respect to current vaccines and neutralizing antibodies (NAbs). How naturally occurring spike mutations affect the infectivity and antigenicity of VOCs remains to be investigated. The entry efficiency of individual spike mutations was determined in vitro using pseudotyped viruses.

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Naturally occurring spike mutations influence the infectivity and immunogenicity of SARS-CoV-2 - Cellular & Molecular Immunology

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Naturally occurring spike mutations influence the infectivity and immunogenicity of SARS-CoV-2 - Cellular & Molecular Immunology

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