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Intralesional TLR4 agonist treatment strengthens the organ defense against colonizing cancer cells in the brain - Oncogene

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Intralesional TLR4 agonist treatment strengthens the organ defense against colonizing cancer cells in the brain - Oncogene

Brain metastasis in breast cancer remains difficult to treat and its incidence is increasing. Therefore, the development of new therapies is of utmost clinical relevance. Recently, toll-like receptor (TLR) 4 was correlated with IL6 expression and poor prognosis in 1 215 breast cancer primaries. In contrast, we demonstrated that TLR4 stimulation reduces microglia-assisted breast cancer cell invasion.

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health tlr4 agonists cancer cell brain cancer cell cell biology biology microbiology

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Intralesional TLR4 agonist treatment strengthens the organ defense against colonizing cancer cells in the brain - Oncogene

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Intralesional TLR4 agonist treatment strengthens the organ defense against colonizing cancer cells in the brain - Oncogene

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