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Hemipiperazines as peptide-derived molecular photoswitches with low-nanomolar cytotoxicity - Nature Communications

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Hemipiperazines as peptide-derived molecular photoswitches with low-nanomolar cytotoxicity - Nature Communications

Molecular photoswitches transform light energy into reversible structural changes. Their combination with known pharmacophores often allows for photomodulation of the biological activity. The effort to apply such compounds in photopharmacology as light-activated pro-drugs is, however, hampered by serious activity reduction upon pharmacophore modifications, or limited biostability.

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Hemipiperazines as peptide-derived molecular photoswitches with low-nanomolar cytotoxicity - Nature Communications

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Hemipiperazines as peptide-derived molecular photoswitches with low-nanomolar cytotoxicity - Nature Communications

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