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Parallel pathways for serotonin biosynthesis and metabolism in C. elegans - Nature Chemical Biology

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Parallel pathways for serotonin biosynthesis and metabolism in C. elegans - Nature Chemical Biology

The neurotransmitter serotonin plays a central role in animal behavior and physiology, and many of its functions are regulated via evolutionarily conserved biosynthesis and degradation pathways. Here we show that in Caenorhabditis elegans, serotonin is abundantly produced in nonneuronal tissues via phenylalanine hydroxylase, in addition to canonical biosynthesis via tryptophan hydroxylase in neurons.

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Parallel pathways for serotonin biosynthesis and metabolism in C. elegans - Nature Chemical Biology

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Parallel pathways for serotonin biosynthesis and metabolism in C. elegans - Nature Chemical Biology

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