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Delineating cooperative effects of Notch and biomechanical signals on patterned liver differentiation - Communications Biology

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Delineating cooperative effects of Notch and biomechanical signals on patterned liver differentiation - Communications Biology

Controlled in vitro multicellular culture systems with defined biophysical microenvironment have been used to elucidate the role of Notch signaling in the spatiotemporal regulation of stem and progenitor cell differentiation. In addition, computational models incorporating features of Notch ligand-receptor interactions have provided important insights into Notch pathway signaling dynamics.

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Delineating cooperative effects of Notch and biomechanical signals on patterned liver differentiation - Communications Biology

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Delineating cooperative effects of Notch and biomechanical signals on patterned liver differentiation - Communications Biology

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