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SHOCing RAF into action - Nature Structural & Molecular Biology

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SHOCing RAF into action - Nature Structural & Molecular Biology

Recent structures of the three-way complex formed by the scaffold protein SHOC2, the small G protein M-RAS and protein phosphatase 1 (PP1) provide a tantalizing insight into the activation of RAF, the oncogenic kinase and downstream effector of RAS that drives cell proliferation and survival.

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SHOCing RAF into action - Nature Structural & Molecular Biology

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SHOCing RAF into action - Nature Structural & Molecular Biology

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