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Clinically relevant germline variants in allogeneic hematopoietic stem cell transplant recipients - Bone Marrow Transplantation

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Clinically relevant germline variants in allogeneic hematopoietic stem cell transplant recipients - Bone Marrow Transplantation

Allogeneic hematopoietic stem cell transplantation (HSCT) provides patients with severe hematologic disease a well-established potential for curation. Incorporation of germline analyses in the workup of HSCT patients is not a common practice. Recognizing rare harmful germline variants may however affect patients' pre-transplantation care, choice of the stem cell donor, and complication risks. We analyzed a population-based series of germline exome data of 432 patients who had undergone HSCT.

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Clinically relevant germline variants in allogeneic hematopoietic stem cell transplant recipients - Bone Marrow Transplantation

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Clinically relevant germline variants in allogeneic hematopoietic stem cell transplant recipients - Bone Marrow Transplantation

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