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A phosphoinositide signalling pathway mediates rapid lysosomal repair - Nature

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A phosphoinositide signalling pathway mediates rapid lysosomal repair - Nature

Lysosomal dysfunction has been increasingly linked to disease and normal ageing1,2. Lysosomal membrane permeabilization (LMP), a hallmark of lysosome-related diseases, can be triggered by diverse cellular stressors3. Given the damaging contents of lysosomes, LMP must be rapidly resolved, although the underlying mechanisms are poorly understood.

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A phosphoinositide signalling pathway mediates rapid lysosomal repair - Nature

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A phosphoinositide signalling pathway mediates rapid lysosomal repair - Nature

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