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Identification of trypsin-degrading commensals in the large intestine - Nature

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Identification of trypsin-degrading commensals in the large intestine - Nature

Increased levels of proteases, such as trypsin, in the distal intestine have been implicated in intestinal pathological conditions1–3. However, the players and mechanisms that underlie protease regulation in the intestinal lumen have remained unclear. Here we show that Paraprevotella strains isolated from the faecal microbiome of healthy human donors are potent trypsin-degrading commensals.

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Identification of trypsin-degrading commensals in the large intestine - Nature

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Identification of trypsin-degrading commensals in the large intestine - Nature

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