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Atypical behavioral and thermoregulatory circadian rhythms in mice lacking a microbiome - Scientific Reports

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Atypical behavioral and thermoregulatory circadian rhythms in mice lacking a microbiome - Scientific Reports

Trillions of microbial oscillators reside throughout the mammalian body, yet their contributions toward fundamental features of host circadian rhythms (CRs) have not been characterized. Here, we demonstrate that the microbiome contributes to host CRs in activity and thermoregulation. Mice devoid of microbes (germ-free, GF) exhibited higher-amplitude CRs in a light–dark cycle and longer circadian periods in constant darkness.

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Atypical behavioral and thermoregulatory circadian rhythms in mice lacking a microbiome - Scientific Reports

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Atypical behavioral and thermoregulatory circadian rhythms in mice lacking a microbiome - Scientific Reports

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