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Immunogenicity to COVID-19 mRNA vaccine third dose in people living with HIV - Nature Communications

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Immunogenicity to COVID-19 mRNA vaccine third dose in people living with HIV - Nature Communications

In order to investigate safety and immunogenicity of SARS-CoV-2 vaccine third dose in people living with HIV (PLWH), we analyze anti-RBD, microneutralization assay and IFN-γ production in 216 PLWH on ART with advanced disease (CD4 count <200 cell/mm3 and/or previous AIDS) receiving the third dose of a mRNA vaccine (BNT162b2 or mRNA-1273) after a median of 142 days from the second dose. Median age is 54 years, median CD4 nadir 45 cell/mm3 (20–122), 93% HIV-RNA < 50 c/mL.

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Immunogenicity to COVID-19 mRNA vaccine third dose in people living with HIV - Nature Communications

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Immunogenicity to COVID-19 mRNA vaccine third dose in people living with HIV - Nature Communications

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