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Loureirin B downregulates osteoclast differentiation of bone marrow macrophages by targeting the MAPK signaling pathway - Scientific Reports
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Excessive absorption of osteoclasts will break the balance between osteoclasts and osteoblasts, leading to bone loss, decreased bone density, and increased bone fragility. We have shown that Loureirin B (LrB) can inhibit osteoclasts. In this study, we demonstrated the targeting-inhibitory mechanism of LrB acting on osteoclast precursor.
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