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LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages - Nature

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LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages - Nature

The mammalian immune system uses various pattern recognition receptors to recognize invaders and host damage and transmits this information to downstream immunometabolic signalling outcomes. Laccase domain-containing 1 (LACC1) protein is an enzyme highly expressed in inflammatory macrophages and serves a central regulatory role in multiple inflammatory diseases such as inflammatory bowel diseases, arthritis and clearance of microbial infection1–4.

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LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages - Nature

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LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages - Nature

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