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Red blood cell distribution width is associated with increased interactions of blood cells with vascular wall - Scientific Reports

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Red blood cell distribution width is associated with increased interactions of blood cells with vascular wall - Scientific Reports

The mechanism underlying the association between elevated red cell distribution width (RDW) and poor prognosis in variety of diseases is unknown although many researchers consider RDW a marker of inflammation. We hypothesized that RDW directly affects intravascular hemodynamics, interactions between circulating cells and vessel wall, inducing local changes predisposing to atherothrombosis. We applied different human and animal models to verify our hypothesis.

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Red blood cell distribution width is associated with increased interactions of blood cells with vascular wall - Scientific Reports

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Red blood cell distribution width is associated with increased interactions of blood cells with vascular wall - Scientific Reports

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