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Spatially resolved clonal copy number alterations in benign and malignant tissue - Nature

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Spatially resolved clonal copy number alterations in benign and malignant tissue - Nature

Defining the transition from benign to malignant tissue is fundamental to improving early diagnosis of cancer1. Here we use a systematic approach to study spatial genome integrity in situ and describe previously unidentified clonal relationships. We used spatially resolved transcriptomics2 to infer spatial copy number variations in >120,000 regions across multiple organs, in benign and malignant tissues.

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Spatially resolved clonal copy number alterations in benign and malignant tissue - Nature

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Spatially resolved clonal copy number alterations in benign and malignant tissue - Nature

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