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Sensing of the non-essential amino acid tyrosine governs the response to protein restriction in Drosophila - Nature Metabolism

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Sensing of the non-essential amino acid tyrosine governs the response to protein restriction in Drosophila - Nature Metabolism

The intake of dietary protein regulates growth, metabolism, fecundity and lifespan across various species, which makes amino acid (AA)-sensing vital for adaptation to the nutritional environment. The general control nonderepressible 2 (GCN2)-activating transcription factor 4 (ATF4) pathway and the mechanistic target of rapamycin complex 1 (mTORC1) pathway are involved in AA-sensing.

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Sensing of the non-essential amino acid tyrosine governs the response to protein restriction in Drosophila - Nature Metabolism

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Sensing of the non-essential amino acid tyrosine governs the response to protein restriction in Drosophila - Nature Metabolism

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