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Activity of singly and doubly modified derivatives of C20-epi-salinomycin against Staphylococcus strains - The Journal of Antibiotics

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Activity of singly and doubly modified derivatives of C20-epi-salinomycin against Staphylococcus strains - The Journal of Antibiotics

Natural polyether ionophore salinomycin (Sal) has been widely used in veterinary medicine as an antibiotic effective in the treatment of coccidian protozoa and Gram-positive bacteria. Moreover, chemical modification of the Sal structure has been found to be a promising strategy to generate semisynthetic analogs with biological activity profiles improved relative to those of the native compound.

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Activity of singly and doubly modified derivatives of C20-epi-salinomycin against Staphylococcus strains - The Journal of Antibiotics

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Activity of singly and doubly modified derivatives of C20-epi-salinomycin against Staphylococcus strains - The Journal of Antibiotics

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