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Lymphocyte subsets in Atlantic cod (Gadus morhua) interrogated by single-cell sequencing - Communications Biology

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Lymphocyte subsets in Atlantic cod (Gadus morhua) interrogated by single-cell sequencing - Communications Biology

Atlantic Cod (Gadus morhua) has lost the major histocompatibility complex class II presentation pathway. We recently identified CD8-positive T cells, B cells, and plasma cells in cod, but further characterisation of lymphocyte subsets is needed to elucidate immune adaptations triggered by the absence of CD4-positive T lymphocytes. Here, we use single-cell RNA sequencing to examine the lymphocyte heterogeneity in Atlantic cod spleen.

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Lymphocyte subsets in Atlantic cod (Gadus morhua) interrogated by single-cell sequencing - Communications Biology

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Lymphocyte subsets in Atlantic cod (Gadus morhua) interrogated by single-cell sequencing - Communications Biology

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