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Association of treatment-emergent symptoms identified by patient-reported outcomes with adjuvant endocrine therapy discontinuation - npj Breast Cancer

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Association of treatment-emergent symptoms identified by patient-reported outcomes with adjuvant endocrine therapy discontinuation - npj Breast Cancer

Many patients discontinue endocrine therapy for breast cancer due to intolerance. Identification of patients at risk for discontinuation is challenging. The minimal important difference (MID) is the smallest change in a score on a patient-reported outcome (PRO) that is clinically significant. We evaluated the association between treatment-emergent symptoms detected by worsening PRO scores in units equal to the MID with discontinuation.

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Association of treatment-emergent symptoms identified by patient-reported outcomes with adjuvant endocrine therapy discontinuation - npj Breast Cancer

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Association of treatment-emergent symptoms identified by patient-reported outcomes with adjuvant endocrine therapy discontinuation - npj Breast Cancer

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