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Management challenges and therapeutic advances in congenital adrenal hyperplasia - Nature Reviews Endocrinology

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Management challenges and therapeutic advances in congenital adrenal hyperplasia - Nature Reviews Endocrinology

Treatment for congenital adrenal hyperplasia (CAH) was introduced in the 1950s following the discovery of the structure and function of adrenocortical hormones. Although major advances in molecular biology have delineated steroidogenic mechanisms and the genetics of CAH, management and treatment of this condition continue to present challenges. Management is complicated by a combination of comorbidities that arise from disease-related hormonal derangements and treatment-related adverse effects.

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Management challenges and therapeutic advances in congenital adrenal hyperplasia - Nature Reviews Endocrinology

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