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Rixosomal RNA degradation contributes to silencing of Polycomb target genes - Nature

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Rixosomal RNA degradation contributes to silencing of Polycomb target genes - Nature

Polycomb repressive complexes 1 and 2 (PRC1 and PRC2) are histone-modifying and -binding complexes that mediate the formation of facultative heterochromatin and are required for silencing of developmental genes and maintenance of cell fate1–3. Multiple pathways of RNA decay work together to establish and maintain heterochromatin in fission yeast, including a recently identified role for a conserved RNA-degradation complex known as the rixosome or RIX1 complex4–6.

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Rixosomal RNA degradation contributes to silencing of Polycomb target genes - Nature

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Rixosomal RNA degradation contributes to silencing of Polycomb target genes - Nature

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